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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
experimental dates: 10-25 May 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. No deviation was reported. The substance is adequately characterised. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
27th July 1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
Regulation (EC) No 440/2008
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. certificate)
Remarks:
Swiss GLP compliance programme (inspected on November 15 and 16, 2011/ signed on May 01, 2012)
Type of method:
method to determine freezing temperature
Remarks:
BS4633: Method for the Determination of Crystallizing Point
Specific details on test material used for the study:
STORAGE CONDITIONS OF TEST MATERIAL
Refrigerator (between 0 and 10 °C under nitrogen)
Key result
Melting / freezing pt.:
9 °C

Table 4.2/1: Determinations 1 and 2

Determination 1

Time (s)

Temperature (K)

Determination 2

Time (s)

Temperature (K)

0

294

0

296

30

292

30

293

60

286

60

290

90

284

90        

286

120

281

120

281

150

277

150

279

180

274

180

276

210

272

210

273

240

272

240

271

270

271

270

268

300

270

300

266

330

268

330

264

360

267

360

265

390

266

390

265

420

264

420

264

450

264

450

264

480

264

480

264

510

264

-

-

 

Observations: Test substance changed in appearance during cooling.

The freezing temperature of test substance has been determined to be 9 ± 0.5 °C (264 ± 0.5 K).

Executive summary:

The freezing point of the test substance was determined according to OECD 102/EU A1 guideline, using BS4633 method for the determination of crystallizing point.

The determination was carried out in duplicate and the mean final temperature was retained.

 

The freezing temperature of test substance has been determined to be 9 ± 0.5 °C (264 ± 0.5 K).

Description of key information

The freezing point (transition from liquid to solid) was measured at 9°C.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
9 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC/BS method and under GLP, is available. It is considered as a key study, and the result is retained as key data.