Registration Dossier

Administrative data

Endpoint:
sub-chronic toxicity: other route
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary literature / original data/study not available / peer-reviewed
Justification for type of information:
Read across is based on the category approach. Please refer to attached category document.

Data source

Reference
Reference Type:
secondary source
Title:
Triethylene Glycol. Review of Phase IV response submissions in support of FIFRA 88.
Author:
EPA
Year:
1993

Materials and methods

GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
monkey
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
other: inhalative and orally
Duration of treatment / exposure:
24 months

Results and discussion

Results of examinations

Details on results:
Monkeys were exposed continuously to saturated/near saturated concentrations of TEG vapors or orally in egg nog of 50 (0.25 cc) - 100 (0.5 cc) times the glycol the animals could absorb by breathing air saturated with glycol, did not adversely effect either the body physiological functions or the organ histpathology.

Effect levels

Basis for effect level:
other: see 'Remark'
Remarks on result:
not measured/tested
Remarks:
Effect level not specified

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion