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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994
Report date:
1994

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
Version / remarks:
1984
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
4-amino-N-(4-amino-6-oxo-5H-pyrimidin-2-yl)benzenesulfonamide
EC Number:
605-738-2
Cas Number:
174863-37-7
Molecular formula:
C10H11N5O3S
IUPAC Name:
4-amino-N-(4-amino-6-oxo-5H-pyrimidin-2-yl)benzenesulfonamide
Test material form:
other:
Remarks:
paste

Test organisms

Test organisms (species):
Daphnia magna

Study design

Total exposure duration:
24 h

Results and discussion

Effect concentrations
Key result
Duration:
24 h
Dose descriptor:
EC50
Effect conc.:
330 mg/L

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The acute toxicity of the test item to Daphnia magna was determined in a 24-hour static test according to the OECD Guideline for Testing of Chemicals No. 202, (1984), resulting in a 24-hour LC50 = 330 mg/L