Benzyltoluene

Direct observations: clinical cases, poisoning incidents and other

Administrative data

Endpoint:

direct observations: clinical cases, poisoning incidents and other

Type of information:

other: human exposure data

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Conform internal company data

Data source

Reference

Reference Type:

other company data

Title:

Unnamed

Year:

1993

Report date:

1993

Materials and methods

Study type:

other: accidental exposure

Endpoint addressed:

eye irritation

Test material

Test material information

Constituent 1

Reference substance name:

no data available

IUPAC Name:

no data available

Details on test material:

Name of the product: Jarylec C 100, Benzyltoluène, Dibenzyltoluène

Method

Type of population:

occupational

Subjects:

- Number of subjects exposed: 1
- Sex: F
- Age: not known
- Race: not indicated
- Known diseases: not known

Ethical approval:

not specified

Route of exposure:

ocular

Reason of exposure:

unintentional, occupational

Exposure assessment:

not specified

Details on exposure:

At the time of the disassembling of the measuring cell, operation which consists in unscrewing a PVC flask in order to change the electrode, a part of this cell broke. The person received a splashing of Jarylec on the face and especially on the eyes.

Examinations:

Eye and skin examinations

Medical treatment:

Following incindent, the woman involved abundantly rinsed her eyes with water and soap during 10 minutes in order to dilute the product. Marked burning of the eyes and around was then observed and she was taken to the infirmary.
Her eyes had become bloodstained. The nurse then put lotion on the eyes and rinsed them with water during 10 minutes. Eye lotion was then used to calm irritation again. Finally, cream containing trolamine was appied on the skin around the eyes.

Results and discussion

Clinical signs:

Marked burning and redness of the eyes and around just following incident.
15 minutes following treatment at the infirmary: redness of the eyes was decreased but eyes were still paintful.
One day following incident, eyes were in a well state, but some irrtation was still present around the eyes.
No more information is available following this date.

Outcome of incidence:

Marked burning and redness of the eyes and around just following incident.
15 minutes following treatment at the infirmary: redness of the eyes was decreased but eyes were still paintful.
One day following incident, eyes were in a well state, but some irrtation was still present around the eyes.
No more information is available following this date.

Applicant's summary and conclusion

Conclusions:

In this case study, Jarylec C 100 was found to be severely irritating to the eye and irritating to the skin of the worker involved in the incident. The effects on eyes were observed to be reversible rapidly, while effects on skin decreased more slowly.

Executive summary:

A female worker received a splashing of Jarylec C 100 containing both benzyltoluene and dibenzyltoluene on the face and eyes. Marked burning of the eyes and around was observed. Eyes were then immediately rinsed during 10 minutes, followed by sequence of eye lotion application and rinsing with water at the infirmary. Cream was also applied on skin at the infirmary.

Fiteen minutes after treatment, redness of the eyes had decreased but eyes were still paintful. One day following incident, eyes were in a well state, but some irrtation was still present around the eyes. No more information is available following this date.