Benzyltoluene

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 28th March to 5th May 1995

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

yes

Remarks:

14C-radiolabelled material was used; pH not measured; no preliminary study.

GLP compliance:

not specified

Type of method:

column elution method

Water solubility:

38 µg/L

Temp.:

20 °C

pH:

7

Remarks on result:

other: No pH check due to system design

Details on results:

Two assays were conducted:

Assay 1:
Temperature: 19.9 - 21.1°C
Water solubility: 46.3 +/- 0.56 µg/L
Time to attain saturation plateau = 1230 hours

Assay 2:
Temperature: 19.5 - 21.0°C
Water solubility: 64.9 +/- 1.13 µg/L
Time to attain saturation plateau = 1290 hours

The difference between assay results was 17.5%. Therefore, assays agreed with a repeatability of less than 30%

Conclusions:

Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The substance was found to be practically insoluble in water. The water solubility was found to be 38 µg/L.

Executive summary:

The water solubility of a mixture of benzyltoluene and dibenzyltoluene was determined according to EU Method A.6 (column elution method) using radioactive material. It was found to be 56 µg/L. As another study as shown that water solubility of dibenzyltoluene is 18 µg/L, it can be concluded that solubility of benzyltoluene in pure water is 38 µg/L (at 20°C).

Description of key information

A good quality study shows that solubility of benzyltoluene in pure water is 38 µg/L at 20°C

Key value for chemical safety assessment

Water solubility:

0.038 mg/L

at the temperature of:

20 °C

Additional information

The key study has been carried out (according to EC method A.6) on a mixture of benzyltoluene (3/4) and dibenzyltoluene (1/4). The measured solubility was 56 µg/L. As it is known from another experiment carried out in same conditions that solubility of pure dibenzyltoluene was 18 µg/L, it can be concluded that 38 µg/L on the present study can be attributed to benzyltoluene.