Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Justification for classification or non-classification

No classification is proposed for carcinogenicity based on a lack of data.

Additional information

TNS did not produce mutagenicity or genetic damage when tested in bacterial and mammalian cell cultures or in laboratory animals. The aqueous dispersion of TNS (~20% solids and~80% water) was administered directly in these studies without correction for active ingredient since the product does not exist as TNS alone and is always transported and used as the aqueous dispersion. Carcinogenicity via genetic mechanisms is not predicted. The lack of active genetic effects supports the position that carcinogenicity is not likely a concern with this test substance.