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Reference
Endpoint:
adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Study period:
June 15, 2016 - Dec 06, 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
Version / remarks:
OECD 121:2001
Deviations:
no
GLP compliance:
yes
Type of method:
HPLC estimation method
Media:
soil/sewage sludge
Details on study design: HPLC method:
- Apparatus: Agilent-1200 Series High Performance Liquid Chromatography
- Type, material and dimension of analytical (guard) column: BDS HYPERSIL Cyano Column, 5μm, 150 × 4.6 mm (Thermo)
- Detection system: Agilent-1260 Infinity Photodiode Array Detector
Computational methods:
Aglient ChemStation Rev. B.0401 electronic data software was used for HPLC/PDA control sysytem, data collection and data processing.
Key result
Type:
log Koc
Remarks:
on sewage suldge
Value:
1.97
Key result
Type:
log Koc
Remarks:
on soil
Value:
2.37

Table 1: The logarithm of adsorption coefficient (log Koc) on sewage sludge and on soil and the logarithm of capacity factor (log K’) of control article and reference article.

Article Name

Log Koc

Retention time (min)

Average retention time (min)

Capacity factor

(K’)

Log K’

Sewage sludge

Soil

t1

t2

Control article

Formamide

-

-

3.021

3.028

3.025

NA

NA

Reference article

Acetanilide

1.52

1.26

4.924

4.931

4.928

0.629

-0.201

Atrazine

1.66

1.81

8.005

8.005

8.005

1.647

0.217

Monuron

1.46

1.99

7.660

7.664

7.662

1.533

0.186

Phenanthrene

4.35

4.09

13.525

13.519

13.522

3.471

0.540

Benzonic acid phenylester

3.26

2.87

11.484

11.473

11.479

2.795

0.446

Fenthion

3.75

3.31

13.957

13.952

13.955

3.614

0.558

2,5-dichloroaniline

2.45

2.55

8.580

8.579

8.580

1.837

0.264

NA: Not application

Table 2: Retention time and capacity factor (K’) of test article Everlan SL65.

Peak

Retention time (min)

Average retention time

Average capacity factor (K’)

Log average capacity factor (log K’)

t1

t2

1

8.411

8.394

8.403

1.778

0.250

Table 3: The adsorption coefficient (Koc) on sewage sludge and on soil of test article Everlan SL65.

Peak

The logarithm of adsorption coefficient (log KOC)

The adsorption coefficient (KOC)

Area of peak (%)

Sewage sludgea

Soilb

Sewage sludge

Soil

1

1.97

2.31

93.54

205.13

100.00

a: Calibration curve of reference article on sewage sludge was y=0.139x – 0.024, R2= 0.939.

b: Calibration curve of reference article on soil was y=0.330x – 0.513, R2= 0.898

Validity criteria fulfilled:
yes
Conclusions:
According to OECD 121 test method, the adsorption coefficients (KOC) of Everlan SL65 on sewage sludge and on soil were 93.54 and 205.13, respectively.
Executive summary:

This test using the procedures outlined in the SuperLab Study Plan for M62-151100110001EN which is based on the SOP for the OECD 121 (SOPE-507) and OECD 121 (OECD, 2001). The results of this OECD 121 test for Everlan SL65show that all validity criteria were met. The adsorption coefficients (KOC) of Everlan SL65 on sewage sludge and on soil were 93.54 and 205.13, respectively.

Description of key information

Respectively, the Log adsorption coefficients (Log KOC) of Everlan SL65 on sewage sludge and on soil were 1.97 and 2.31 (OECD TG 121). The test is not done in the water. The estimated Log Koc water is 2.0.

Key value for chemical safety assessment

Koc at 20 °C:
100

Other adsorption coefficients

Type:
log Kp (solids-water in activated sewage sludge)
Value in L/kg:
1.97
at the temperature of:
20 °C

Other adsorption coefficients

Type:
log Kp (solids-water in soil)
Value in L/kg:
2.31
at the temperature of:
20 °C

Additional information

All of the articles were ran in duplicate and the difference of log KOC of test article between duplicate were < 0.25. In order to confirm retention times of test article had not drifted on HPLC analysis, formamide as the control article was analyze before and after the test artic. All test validity criteria were met. The adsorption coefficients (KOC) of Everlan SL65 on sewage sludge and on soil were 93.54 and 205.13, respectively.

[LogKoc: 2.0]