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Diss Factsheets

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
flammable solids
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2017-05-09 to 2017-07-06
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.10 (Flammability (Solids))
Version / remarks:
2008
Deviations:
no
GLP compliance:
no
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Thai Hakko Biotechnologies Co., Ltd. / batch 160006
- Expiration date of the lot/batch: retest date 2018-02-22
- Purity test date: 2016-03-08

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: 10 - 25 °C in a tightly closed container, stored in a dry and well ventilated place
- Stability under test conditions: stable
- Solubility and stability of the test substance in the solvent/vehicle: highly soluble
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: n.a.
Key result
Test procedure:
burning rate test over 100 mm length
Remarks on result:
substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period
Interpretation of results:
GHS criteria not met
Conclusions:
The test item is considered to be not flammable.
Executive summary:

The purpose of the study was to evaluate the flammability of the test item L-4-Hydroxyproline.


The test item L-4-Hydroxyproline was used in its initial form. The test item could not be ignited (at the end of the measurement the test item was melted and the colour changing from white to brown was observed) and no smouldering was observed. Therefore, the test item is considered to be not flammable.

Description of key information

Key value for chemical safety assessment

Flammability:
not classified

Additional information

Justification for classification or non-classification

The test item could not be ignited and no smouldering was observed. Therefore, the test item is considered to be not flammable.