Registration Dossier

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
fish early-life stage toxicity
Data waiving:
other justification
Justification for data waiving:
other:

Description of key information

Key value for chemical safety assessment

Additional information

There are no long-term fish studies available for Octadecanoic acid, ester with 2,2'-[oxybis(methylene)]bis[2- (hydroxymethyl)-1,3-propanediol] (CAS 70969-57-2). The chemical safety assessment according to Annex I of Regulation (EC) No 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish. Thus, in accordance to Annex IX, column 2 no further long-term toxicity test to fish is proposed. Available short-term studies for fish, aquatic invertebrates and algae, all indicate no potential for aquatic toxicity. Moreover, no chronic effects were recorded in the long-term toxicity to invertebrates study up to the limit of water solubility. As there was no sign that fish are more sensitive compared to aquatic invertebrates in the available short- and long-term tests, it cannot be expected that a long-term test with fish will generate different results. Thus, based on the above mentioned results, it can be excluded that the target substance will exhibit chronic toxicity to fish up to the limit of water solubility. Hence due to animal welfare reasons and to avoid unnecessary vertebrate tests, no further long-term test with fish was proposed.