2-({3-(octadecanoyloxy)-2,2-bis[[](octadecanoyloxy)methyl]propoxy}methyl)-2-[[](octadecanoyloxy)methyl]propane-1,3-diyl dioctadecanoate

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

15 Mar - 5 Oct 2017

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Key result

Water solubility:

< 0 mg/L

Conc. based on:

test mat.

Temp.:

20 °C

pH:

ca. 7

The Water solubility test was started at 14:30 hrs, 5 July 2017 and the three 30 mL samples taken at 09:00 hrs, 6 July 2017. The test temperature was 20 ± 0.5 °C (min 19.9 °C, max 20.3 °C and mean 20.1 °C).

The theoretical concentration at the time of sampling was 556.05 µg/mL, taking into account both dissolved and undissolved particles.

At a concentration of 0.000172 µg/mL; the first test sample recorded a turbidity of 0.070 NTU and the second and third samples at 0.0000172 µg/mL with a turbidity of 0.067 and 0.060 NTU respectively. It was therefore concluded that the water solubility is <0.00017 µg/mL.

Description of key information

Water solubility: < 1.7E-4 mg/L at 20 °C, pH ca. 7 (similar to OECD guideline 105, flask method)