Registration Dossier
Registration Dossier
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EC number: 203-636-9 | CAS number: 108-99-6
Biodegradation in soil
Administrative data
Link to relevant study record(s)
Description of key information
Waiver: soil simulation testing is not required since 3-methylpyridine has a low potential for adsorption to soil and has been shown to readily biodegradable.
Supporting studies do not indicate the need for soil simulation testing. The study by Sims and Sommers (1985) showed that pyridine was degraded to levels below the limit of detection after 8 days under aerobic conditions. Similar results were reported by Naik et al. (1972), who showed that pyridine was able to be degraded by microorganisms in fertile garden soil within approximately 1-2 months. Anaerobes degraded pyridine more rapidly than aerobic bacteria. A half-life in soil was not reported.
Key value for chemical safety assessment
Additional information
According to Regulation (EC) No.1907/2006, Annex IX, Section 9.2.1.3, Column 2, soil simulation testing for compounds with a high potential for adsorption to soil does not need to be conducted if the substance is readily biodegradable. 3 -Methylpyridine has been shown to have a low potential for adsorption to soil and has been shown to be readily biodegradable.
In addition, the non-guideline study by Kaiser et al. (1992) demonstrated the complete mineralisation of 3-methylpyridine to carbon dioxide and ammonia after 30 days of incubation under anaerobic conditions. A non-guideline study by Bollag and Kaiser (1990) showed complete degradation of 3-methylpyridine under various aerobic conditions, with variant temperature, pH, sodium chloride concentration, phosphorous concentration, nitrogen concentration and alternate carbon substrates. A half-life in soil was not reported.
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