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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
This study was conducted between 20 September 2016 and 20 January 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study is considered to be a reliability 1 as it has been conducted according to OECD TG 102 using the method to determine the freezing point and in compliance with GLP.
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
EC No. 440/2008 of 30 May 2008
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
27 July 2005
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
method to determine freezing temperature
Key result
Melting / freezing pt.:
> 37.2 - < 39.4 °C
Decomposition:
no
Sublimation:
no
Key result
Melting / freezing pt.:
> 310.3 - < 312.5 K
Decomposition:
no
Sublimation:
no

Discussion

The test item was analysed from sub ambient temperatures in order to obtain a stable baseline prior to the monitoring of the test item from ambient temperatures.

Determinations 1 and 2 were used to determine a suitable temperature range for the melting point determination, therefore, as the enthalpy of the change at approximately 40 °C is much smaller than the later endotherm, no integration was carried out.

As the test item shows a range of melting temperature the final results is reported as a melting range.

Conclusions:
The melting/freezing point of the test item was determined to be 37.2 - 39.4°C in a reliable GLP study according to OECD TG 102 using the the method to determine melting/freezing temperature.
Executive summary:

The general physico-chemical properties of Formaldehyde, reaction products with aniline, 4,4'-methylenebis[phenol] have been determined.

Melting/Freezing Point. In the range 37.2 to 39.4 °C (310.3 to 312.5 K) by differential scanning calorimetry using a method designed to be compatible with Method A.1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Description of key information

Melting/Freezing Point. In the range 37.2 to 39.4 °C (310.3 to 312.5 K) by differential scanning calorimetry using a method designed to be compatible with Method A.1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
37.2 °C

Additional information