Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Partly cited from SIAR to SIAM 19 (Berlin, 19-22 October 2004):

In a guinea pig maximization test according to OECD TG 406 (1981), none of the 20 test animals showed a positive reaction 24 as well as 48 hours after challenge with the pure substance. Positive controls were not used in this study (Hüls AG, 1989).


Migrated from Short description of key information:
Partly cited from SIAR to SIAM 19 (Berlin, 19-22 October 2004):
1,2,3,4-Tetrahydronaphthalene was not sensitizing in a guinea pig maximization test, in which no
positive controls were used (OECD TG 406, 1981).

Justification for classification or non-classification

1,2,3,4-Tetrahydronaphthalene was not sensitizing in a guinea pig maximization test, in which no positive controls were used (OECD TG 406, 1981).