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Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Tetralinvergiftung. Offizielles Protokoll der Gesellschaft der Ärzte in Wien
Author:
Arnstein A
Year:
1922
Bibliographic source:
Wien. Klin. Wschr. 21, S. 88

Materials and methods

Study type:
clinical case study

Test material

Reference
Name:
Unnamed
Type:
Constituent

Method

Subjects:
- Persons: 2 painters
Examinations:
- Exposure: Painting for three days with tetralin-containing varnishes in  a poorly ventilated area

Results and discussion

Results of examinations:
- Main symptom: Dark green colored urine
- Other symptoms: intense irritation of mucous membranes, profuse  lacrimation, headache, and stupor
- Reversibility: Complete within few days

Applicant's summary and conclusion