Registration Dossier

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

The BCF was determined by QSAR estimation (Degussa, 2004). Considering a Log Pow of 3.78 for Tetrahydronaphthalene, the BCF for fish was 162.4 L/kg (calculated with BCFWIN v 2.14 as integrated in EPIWIN V3.10) and 326 and 1500 for Pimephales promelas and Leuciscus idus, respectively (according to EU Technical Guidance Document on Risk  Assessment of Chemical Substances  following European Regulations and  Directives, 2nd Edition (2003)).
There is no measured data on bioconcentration for tetrahydronaphthalene available. Based on the measured partition coefficient n-octanol/water (log Kow = 3.78) in the study of Hüls (1989), tetrahydronaphthalene may have a potential for bioaccumulation.
However animal experiments in rats investigating toxicokinetics upon single or repeated oral dosing indicated rapid absorption, and elimination mainly via urine. Tetrahydronaphthalin is metabolized by hydroxylation at the non-aromatic portion of the molecule. The metabolites are excreted mainly (generally > 90 %) as glucuronides. According to mammalian toxicity data, tetrahydronaphthalene is not classified as very toxic (T+), Toxic (T) or harmful (Xn) and does not carry the risk phrases R48, R60, R62, R63 or R64. R48 or R60-R64 present in the classification of the substance. Moreover tetrahydronaphthalene revealed to be readily biodegradable.
Additionally according to the use information the substance is to be manufactured and used in dry processes and only in closed systems. Sampling, filling and transport also takes place only in closed systems. Therefore there will be no exposure to the environment (please refer to point 9 of CSR).
Therefore, for all the reasons stated above, tetrahydronaphthalene is not expected to accumulate in the environment and no estimation of bioaccumulation will be required.

Key value for chemical safety assessment

Additional information