Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

Currently viewing:

Administrative data

Link to relevant study record(s)

bioaccumulation in aquatic species: fish
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Accepted calculation method
Principles of method if other than guideline:
Method 1: calculation with BCFWIN v2.14 as integrated in EPIWIN v3.10, Syracuse Research Center / U.S. EPA
Method 2: calculation of BCF from log Kow according to EU TGD (see data source)
Test organisms (species):
other: QSAR estimate
Key result
162.4 - 1 514 dimensionless

- Calculation with BCFWIN v2.14 as integrated in EPIWIN v3.10, Syracuse  Research Center / U.S. EPA: 
  BCF = 162.4
- Calculation according to EU Technical Guidance Document on Risk  Assessment of Chemical Substances 

following European Regulations and  Directives, 2nd Edition (2003), chapter
  BCF (Pimephales promelas) = 326
  BCF (Lumbricus terrestris) = 1514

Description of key information

The BCF was determined by QSAR estimation (Degussa, 2004). Considering a Log Pow of 3.78 for Tetrahydronaphthalene, the BCF for fish was 162.4 L/kg (calculated with BCFWIN v 2.14 as integrated in EPIWIN V3.10) and 326 and 1500 for Pimephales promelas and Leuciscus idus, respectively (according to EU Technical Guidance Document on Risk Assessment of Chemical Substances following European Regulations and Directives, 2nd Edition (2003)).  

There is no measured data on bioconcentration for tetrahydronaphthalene available. Based on the measured partition coefficient n-octanol/water (log Kow = 3.78) in the study of Hüls (1989), tetrahydronaphthalene may have a potential for bioaccumulation.  

However, animal experiments in rats investigating toxicokinetics upon single or repeated oral dosing indicated rapid absorption, and elimination mainly via urine. Tetrahydronaphthalene is metabolized by hydroxylation at the non-aromatic portion of the molecule. The metabolites are excreted mainly (generally > 90 %) as glucuronides. According to mammalian toxicity data, tetrahydronaphthalene is not classified as toxic. Moreover, tetrahydronaphthalene revealed to be readily biodegradable.  

Additionally, according to the use information, the substance is to be manufactured and used in dry processes and only in closed systems. Sampling, filling and transport also takes place only in closed systems. Therefore, there will be no exposure to the environment (please refer to point 9 of CSR).  

Therefore, for all the reasons stated above, tetrahydronaphthalene is not expected to accumulate in the environment and no estimation of bioaccumulation will be required.

Key value for chemical safety assessment

Additional information