Registration Dossier
Registration Dossier
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EC number: 213-626-6 | CAS number: 995-33-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
72h-EC10and 72h-EC50 for freshwater algae were determined to be 160.5 µg/L and 421.5 µg/L, respectively according to OECD 201 guideline.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 421.5 µg/L
- EC10 or NOEC for freshwater algae:
- 160.5 µg/L
Additional information
The acute toxicity of n-butyl-4,4 -bis(tert-butylperoxy)valerate to freshwater algae was tested using OECD guideline 201 under GLP conditions (Chastenet, 2017).
The concentrations that result in a 10 and 50% reduction in growth rate (72h-ErC10 and 72h-ErC50, respectively) were determined.
As the test item was known to be difficult to dissolve, tests solutions were prepared from dilutions of a saturated solution prepared using slow-stirring conditions described in the OECD 123 guideline.
Chemical analysis of the test item showed the instability of the substance over the 72-hour test period. Based on these results, the exposure concentrations were based on the geometric mean of measured concentrations: 72h-EC10and 72h-EC50 were determined to be 160.5 µg/L and 421.5 µg/L, respectively. The definitive test met the validity criteria of the test guideline.
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