Registration Dossier
Registration Dossier
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EC number: 601-478-9 | CAS number: 117428-22-5
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7840 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- other: Shake flask method
- Key result
- Water solubility:
- 3.25 other: µg/mL
- Conc. based on:
- test mat.
- Incubation duration:
- 3 d
- Temp.:
- 20 °C
- pH:
- 6.5
- Details on results:
- The results showed that the saturation of the test item in the water was achieved by day three. The mean value of water solubility was determined based on the samples from Day 1, 2 and 3. The variation between the two successive samples was lower than the maximum allowed difference of 15% as based on the guidelines.
- Conclusions:
- Water solubility: 3.25 ± 0.17 μg/mL or 0.325 x 10e-2 g/L at 20°C
- Executive summary:
The study was conducted to determine the water solubility of the test substance. The water solubility was determined according to regulatory guidelines: OPPTS 830.7840 (US-EPA), OECD Guideline No. 105 and EEC Method A.6.
The mean water solubility of the test substance in Milli-Q water determined by shake flask method was 3.25 ± 0.17 μg/mL or 0.325 x 10e-2 g/L at 20°C.
Reference
Description of key information
OECD Guideline 105
Key value for chemical safety assessment
- Water solubility:
- 3.25 mg/L
- at the temperature of:
- 20 °C
Additional information
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