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EC number: 601-478-9 | CAS number: 117428-22-5
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- other: Shake flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 3.68
- Temp.:
- 20 °C
- pH:
- 6.93
- Conclusions:
- log Pow: 3.68 ± 0.01 at 20 ± 1°C
- Executive summary:
The study was conducted to determine the partition coefficient of the test substance. The partition coefficient was determined according to regulatory guidelines: OECD Guidelines for the Testing of Chemicals: Partition Coefficient (n-Octanol/Water): Shake Flask Method, Test Guideline 107 and EEC A.8.
The mean partition coefficient, (log Pow) of the test substance was 3.69 ± 0.01, 3.69 ± 0.00 and 3.68 ± 0.01 for octanol-water ratios of 1:1, 1:2 and 2:1, respectively, at 20 ± 1°C.
The overall mean partition coefficient (log Pow) of the test substance was 3.68 ± 0.01 at 20 ± 1°C.
Reference
Description of key information
OECD Guideline 107
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.68
- at the temperature of:
- 20 °C
Additional information
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