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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: OECD Guideline 105
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: EC Method A.6
Deviations:
no
GLP compliance:
yes
Key result
Medium:
other: xylene, 1,2-dichloroethane, acetone and ethyl acetate
Solubility:
> 250 g/kg solvent
Temp.:
20 °C
Key result
Medium:
other: n-heptane
Solubility:
6 g/kg solvent
Temp.:
20 °C
Key result
Medium:
methanol
Solubility:
96 g/kg solvent
Temp.:
20 °C
Test substance stable:
yes
Conclusions:
Solubility of test material at 20°C:
Xylene, 1,2-dichloroethane, acetone and ethyl acetate: >250 g/kg solution (>200 g/L solution)
n-Heptane: 6 g/kg solution (4 g/L solution)
Methanol: 96 g/kg solution (76 g/L solution)
Executive summary:

The solubility of test material at 20°C was >250 g/kg solution (>200 g/L solution) in xylene, 1,2-dichloroethane, acetone and ethyl acetate; 6 g/kg solution (4 g/L solution) in n-heptane and 96 g/kg solution (76 g/L solution) in methanol.

Description of key information

OECD Guideline 105

Key value for chemical safety assessment

Additional information

Solubility of test material at 20°C:

Xylene, 1,2-dichloroethane, acetone and ethyl acetate: >250 g/kg solution (>200 g/L solution)

n-Heptane: 6 g/kg solution (4 g/L solution)

Methanol: 96 g/kg solution (76 g/L solution)