Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

Test substance formulations were not found to be mutagenic in bacteria, and did not induce gene conversion in yeast, chromosome damage in rat liver cells, or gene mutation in mouse lymphoma cells. All results for genotoxic potential were negative.


Short description of key information:
Negative for mutagenicity on bacterial cultures in non-GLP short term in vitro tests (equivalent to OECD 471)
Negative for induction of structural and numerical chromosome aberrations (OECD 473)
Negative for gene mutation in mouse lymphoma cells (OECD 476)

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Test substance formulations were not found to be mutagenic in bacteria, and did not induce gene conversion in yeast, chromosome damage in rat liver cells, or gene mutation in mouse lymphoma cells. All results for genotoxic potential, in prokaryotic and eukaryotic (including mammalian) species were negative. Therefore, in accordance with Directive 67/548/EEC and EC Regulation 1272/2008, no classification is required.