Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: well performed OECD study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report Date:
2014

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
purity: 99.8%

Results and discussion

Water solubility
Water solubility:
48 mg/L
Temp.:
20 °C
pH:
> 8.5 - < 8.6
Details on results:
Three flasks containing approx. 5 g/l test substance in water were stirred for 5 h at 30 °C.
Subsequently the flasks were stirred at 20 °C for 1 day, 2 days and 3 days, respectively.
After each day the content of one flask was filtered through a 0,45 μm membrane filter. The
content of the test substance in the filtrate was determined by UV/VIS spectroscopy.

Flask No. Equilibration time pH Test substance
at 20°C [h] content [mg/L]
1 24 8.6 50
2 48 8.5 48
3 72 8.6 47
mean 48

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility is 48 mg/L at 20°C.
Executive summary:

The water solubility of the substance was determined according to OECD guideline 105 (flask method) and was found to be 48 mg/L at 20°C.