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Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
OECD107

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2016
Report date:
2016

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
GLP compliance:
no
Type of method:
flask method
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Reaction mass of ammonium 4-amino-3-nitrobenzenesulfonate and sodium 4-amino-3-nitrobenzenesulfonate
EC Number:
700-384-6
Cas Number:
82324-60-5
Molecular formula:
C6H5N2O5S.H4N C6H5N2O5S.Na
IUPAC Name:
Reaction mass of ammonium 4-amino-3-nitrobenzenesulfonate and sodium 4-amino-3-nitrobenzenesulfonate
Test material form:
solid: bulk
Specific details on test material used for the study:
Purity: 97,5 % (w/w)

Study design

Analytical method:
other: UV/VIS spectroscopy

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
-2.5
Temp.:
23 °C
pH:
>= 7.6 - <= 8.2
Details on results:
A stock solution of the test substance in n-octanol saturated water was prepared. To 5 ml, 10 ml and 20 ml of the stock solution 10 ml of water saturated n-octanol were added. The two-phase system was shaken vigorously at room temperature (23 °C) for one hour. Subsequently the phases were separated by centrifugation for 20 min at 14500 rpm and the test substance concentration in each phase was determined by UV/VIS spectroscopy.
Stock solution: 763 mg/l

Applicant's summary and conclusion

Conclusions:
The test substance has a log Pow of -2.5 at 23°C.
Executive summary:

The log Pow of the test substance was determined according OECD107. The log Pow at 23 °C is -2.5.