Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

A weight of evidence approach was used to assess the bioaccumulation potential of the registered substance, using QSAR predictions. The relevant estimated BCF values for the registered substance were all comprised between 407 and 4219 L/kg, calculated using the experimental log Kow value at 5.05. Based on these available data, the registered substance seems to be bioaccumulable (log Kow > 4.5 and BCF > 2000 L/kg) but not very bioaccumulable (BCF < 5000 L/kg) according to PBT criteria. However, at pH in the stomach of fish (generally comprised between 2 and 4), hydrolysis of the registered substance occured before biotransformation in liver and the BCF value of the hydrolysis product / metabolite at acid pH (the diol form) is considerably low, at 12.9 L/kg. Therefore, we can conclude that the registered substance is not bioaccumulable.

Additional information