Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-477-1 | CAS number: 65122-06-7
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Justification for type of information:
- Estimated data generated using the EPI Suite model developed by the USEPA.
- Qualifier:
- according to guideline
- Guideline:
- other: Modeling database
- Principles of method if other than guideline:
- HYDROWIN Program (v2.00) from EPI Suite estimation database
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material: 2-[2-[4-[(2-cyanoethyl)methylamino]phenyl]vinyl]-1,3,3-trimethyl-3H-indolium acetate
- IUPAC name: 2-(2-{4-[(2-cyanoethyl)(methyl)amino]phenyl}vinyl)-1,3,3-trimethyl-3H-indolium acetate
- Molecular formula: C23H26N3.C2H3O2
- Molecular weight: 403.5231g/mole
- Smiles : CC(=O)[O-].CC1(C2=CC=CC=C2[N+](=C1C=CC3=CC=C(C=C3)N(C)CCC#N)C)C
- Inchl: 1S/C23H26N3.C2H4O2/c1-23(2)20-8-5-6-9-21(20)26(4)22(23)15-12-18-10-13-19(14-11-18)25(3)17-7-16-24;1-2(3)4/h5-6,8-15H,7,17H2,1-4H3;1H3,(H,3,4)/q+1;/p-1
- Substance type: Organic
- Physical state: Greenish lustourous liquid - Radiolabelling:
- not specified
- Analytical monitoring:
- not specified
- Estimation method (if used):
- HYDROWIN v2.00
- Transformation products:
- not specified
- pH:
- 7
- Temp.:
- 25 °C
- DT50:
- 16.3 d
- Type:
- not specified
- Remarks on result:
- other: other details not available
- pH:
- 8
- Temp.:
- 25 °C
- DT50:
- 1.63 d
- Type:
- not specified
- Remarks on result:
- other: other details not available
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The half life of hydrolysis of test chemical 2-[2-[4-[(2-cyanoethyl)methylamino]phenyl]vinyl]-1,3,3-trimethyl-3H-indolium acetate was estimated to be 16.3 days and 1.63 days at pH 7 and 8 respectively. On the basis of this half life value it can be concluded that test chemical 2-[2-[4-[(2-cyanoethyl)methylamino]phenyl]vinyl]-1,3,3-trimethyl-3H-indolium acetate shows negligible to slow hydrolysis.
- Executive summary:
The half life of hydrolysis od test chemical 2-[2-[4-[(2-cyanoethyl)methylamino]phenyl]vinyl]-1,3,3-trimethyl-3H-indolium acetate (CAS no. 65122 -06 -7) was estimated by using EPI suite (2018). The half life of hydrolysis of test chemical was estimated to be 16.3 days and 1.63 days at pH 7 and 8 respectively. On the basis of this half life value it can be concluded that test chemical 2-[2-[4-[(2-cyanoethyl)methylamino]phenyl]vinyl]-1,3,3-trimethyl-3H-indolium acetate
shows negligible to slow hydrolysis.
Reference
Description of key information
The half life of hydrolysis od test chemical 2-[2-[4-[(2-cyanoethyl)methylamino]phenyl]vinyl]-1,3,3-trimethyl-3H-indolium acetate(CAS no. 65122 -06 -7) was estimated by using EPI suite (2018). The half life of hydrolysis of test chemical was estimated to be 16.3 days and 1.63 days at pH 7 and 8 respectively. On the basis of this half life value it can be concluded that test chemical 2-[2-[4-[(2-cyanoethyl)methylamino]phenyl]vinyl]-1,3,3-trimethyl-3H-indolium acetate
shows negligible to slow hydrolysis.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 16.3
- at the temperature of:
- 25 °C
Additional information
The half life of hydrolysis od test chemical 2-[2-[4-[(2-cyanoethyl)methylamino]phenyl]vinyl]-1,3,3-trimethyl-3H-indolium acetate(CAS no. 65122 -06 -7) was estimated by using EPI suite (2018). The half life of hydrolysis of test chemical was estimated to be 16.3 days and 1.63 days at pH 7 and 8 respectively. On the basis of this half life value it can be concluded that test chemical 2-[2-[4-[(2-cyanoethyl)methylamino]phenyl]vinyl]-1,3,3-trimethyl-3H-indolium acetate
shows negligible to slow hydrolysis.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
