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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2009

Materials and methods

Principles of method if other than guideline:
Data from handbook
GLP compliance:
not specified
Remarks:
Handbook data

Test material

Constituent 1
Chemical structure
Reference substance name:
Thiosemicarbazide
EC Number:
201-184-7
EC Name:
Thiosemicarbazide
Cas Number:
79-19-6
Molecular formula:
CH5N3S
IUPAC Name:
hydrazinecarbothioamide
Test material form:
solid: crystalline

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 9.2 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
Category 2 based on GHS criteria
Conclusions:
The test item has an LD50 oral value of 9.2 mg/kg/bw for rats.
Executive summary:

According the handbook of Enviromental data on Organic chemicals, the test item has an LD50 oral value of 9.2 mg/kg/bw for rats.