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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
documentation insufficient for assessment

Data source

Reference
Reference Type:
review article or handbook
Title:
Unnamed
Year:
2009

Materials and methods

Principles of method if other than guideline:
Data from handbook
GLP compliance:
not specified
Remarks:
Handbook data

Test material

Constituent 1
Chemical structure
Reference substance name:
Thiosemicarbazide
EC Number:
201-184-7
EC Name:
Thiosemicarbazide
Cas Number:
79-19-6
Molecular formula:
CH5N3S
IUPAC Name:
hydrazinecarbothioamide
Test material form:
solid: crystalline

Test animals

Species:
rat
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified

Results and discussion

Effect levels
Key result
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 9.2 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
Category 2 based on GHS criteria
Conclusions:
The test item has an LD50 oral value of 9.2 mg/kg/bw for rats.
Executive summary:

According the handbook of Enviromental data on Organic chemicals, the test item has an LD50 oral value of 9.2 mg/kg/bw for rats.