Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From April 15, 2013 to April 26,2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report Date:
2013

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Type:
impurity
Type:
Constituent
Test material form:
liquid

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
>= 4 - <= 4.3
Temp.:
35 °C
pH:
7

Applicant's summary and conclusion

Conclusions:
The partition coefficient n-octanol/water of Methylionantheme 100% was determined by the Reverse Phase High Performance Liquid Chromatographic Method according to the OECD Guidelines for testing of chemicals, method No 117.
The result is:
Partition coefficient n-octanol/water of Methylionantheme 100%:
Log P(ow)= 4.0, 4.1; 4.2 and 4.3.