Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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Reaction mass of trisodium bis[5-amino-2-(hydroxy-κO)-3-{[1-(hydroxy-κO)-2-naphthyl]diazenyl-κN1}benzenesulfonato(3-)]chromate(3-), trisodium bis[2-(hydroxy-κO)-3-{[1-(hydroxy-κO)-2-naphthyl]diazenyl-κN1}-5-nitrobenzenesulfonato(3-)]chromate(3-) and heptasodium bis[4-(hydroxy-κO)-3-{[2-(hydroxy-κO)-5-nitro-3-sulfophenyl]diazenyl-κN2}-6-(4-sulfoanilino)naphthalene-2-sulfonato(5-)]chromate(7-)
EC number: 944-619-2 | CAS number: -
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- other: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- other: data obtained after Article 25(3) request
- Title:
- Unnamed
- Year:
- 2 017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- Qualifier:
- according to guideline
- Guideline:
- EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Acid Black 173 - Similar Substance 01
- IUPAC Name:
- Acid Black 173 - Similar Substance 01
- Test material form:
- not specified
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
- Remarks:
- HC:NZW
Test system
- Type of coverage:
- semiocclusive
- Vehicle:
- water
- Amount / concentration applied:
- 500 mg
- Duration of treatment / exposure:
- 4 h
- Number of animals:
- 3
Results and discussion
In vivo
Resultsopen allclose all
- Irritation parameter:
- erythema score
- Basis:
- animal: 1, 2, 3
- Time point:
- 24/48/72 h
- Score:
- 0
- Irritation parameter:
- edema score
- Basis:
- animal: 1, 2, 3
- Time point:
- 24/48/72 h
- Score:
- 0
- Other effects:
- None
Applicant's summary and conclusion
- Interpretation of results:
- other: CLP criteria not met
- Conclusions:
- Non skin irritant
- Executive summary:
Method
The substance has been tested for its skin irritation potential according to the OECD guideline 404.
Results
Non skin irritant
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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