Registration Dossier

Physical & Chemical properties

Density

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
density
Remarks:
density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
15 December 2003 to 16 December 2003
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Deviations:
no
GLP compliance:
yes
Type of method:
pycnometer method
Key result
Type:
density
Density:
1.182 g/cm³
Temp.:
24 °C

Results

 Replicate  Density (g/cm³)
 1  1.1816
 2  1.1811
 3  1.1823
 Mean  1.182
 Standard Deviation (SD)  0.0006
Conclusions:
Under the conditions of the test, the density of the test substance was determined to be 1.182 ± 0.0006 g/cm³.
Executive summary:

In a GLP compliant density study conducted in line with OECD Guideline 109, the density of butanoic acid, 4-[[4-[7-chloro-6-(1,1-dimethylethyl)-3H-pyrazolo[1,5-b][1,2,4]triazol-2-yl]phenyl]amino]-4-oxo-, tetradecyl ester was determined using the pycnometer method. The density of the substance was determined to be 1.182 ± 0.0006 g/cm³ at 24 ± 1 ºC.

Description of key information

Key study:- Hoffman (2004a) 'Density' conducted in line with OECD Guideline 109. The density of the test substance was determined to be 1.182 g/cm³ at 24 ± 1 ºC.

Key value for chemical safety assessment

Relative density at 20C:
1.182

Additional information

The key study (Hoffman, 2004a) was performed in compliance with GLP and to the OECD Guideline 109 with a sufficient level of detail to assess the quality of the presented data. The study was performed to a good standard in line with an accepted, standardised guideline and was assigned a reliability score of 1 using the principles for assessing data quality as set out in Klimisch et al. (1997). The density of the test substance was determined to be 1.182 g/cm³ at 24 ± 1 ºC.