Registration Dossier
Registration Dossier
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EC number: 288-422-3 | CAS number: 85721-12-6
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation, other
- Remarks:
- QSAR estimation
- Type of information:
- (Q)SAR
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: QSAR model developed for dyes
- Justification for type of information:
- QSAR predictive models developed for dyes.
Data source
Reference
- Reference Type:
- other: QSAR estimation
- Title:
- Unnamed
- Year:
- 2 017
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- QSAR estimation
- Justification for non-LLNA method:
- -
Test material
- Reference substance name:
- Sodium 3-[[5-[(diethylamino)sulphonyl]-2-methoxyphenyl]azo]-4-hydroxynaphthalene-1-sulphonate
- EC Number:
- 288-422-3
- EC Name:
- Sodium 3-[[5-[(diethylamino)sulphonyl]-2-methoxyphenyl]azo]-4-hydroxynaphthalene-1-sulphonate
- Cas Number:
- 85721-12-6
- Molecular formula:
- C21H23N3O7S2Na
- IUPAC Name:
- sodium 3-[[5-[(diethylamino)sulphonyl]-2-methoxyphenyl]azo]-4-hydroxynaphthalene-1-sulphonate
Constituent 1
Results and discussion
In vitro / in chemico
Results
- Parameter:
- other: skin sensitization
- Value:
- 0
- Vehicle controls validity:
- not applicable
- Negative controls validity:
- not applicable
- Positive controls validity:
- not applicable
- Remarks on result:
- no indication of skin sensitisation
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Not skin sensitizing
- Executive summary:
Based on QSAR estimation, no concern for skin sensitization.
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