Registration Dossier

Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Information from peer reviewed handbook/review.

Data source

Reference
Reference Type:
publication
Title:
Odor as an aid to chemical safety: odor thresholds compared with threshold limit values and volatilities for 214 Industrial chemicals in air and water dilution.
Author:
Amoore JE and Hautala E
Year:
1983
Bibliographic source:
J Appl Toxicol 3, 272-300.

Materials and methods

Type of study / information:
Type: other: Odor threshold

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
TS-Freetext:
Methyl formate.

Results and discussion

Any other information on results incl. tables

RS-Freetext:
Odor threshold in air:  600 ppm; 
Standard error:        2.9
TLV:                   100 ppm
Odor safety factor:    0.17
Odor safety class:     E

Applicant's summary and conclusion

Conclusions:
CL-Freetext:
The odor threshold is higher than the TLV. Therefore,
hazardous concentrations of methylformate are not perceived
by smell.