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Density

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Reference
Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2015-08-27 to 2015-08-28
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.3 (Relative Density)
Qualifier:
according to
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
2012
GLP compliance:
yes (incl. certificate)
Type of method:
pycnometer method
Type:
density
Density:
1.28 g/cm³
Temp.:
19.99 °C
Remarks on result:
other: mean (two samples)
Key result
Type:
relative density
Density:
1.28 other: dimensionless
Temp.:
20 °C

The relative density of two independent samples has been determined with an absolute deviation of 0.0009.

Table 1: Calibration check of the pycnometer

Calibration sphere

Volume nominal [cm^3]

Volume determined [cm^3]

Deviation from nominal Vol [%]

Identification No.: 302, Diameter 41.275

36.81708

36.84320

0.07

 

Table 2: Weight of Scopolamine

Weight No.

Vessel empty [g]

Vessel + test item [g]

Weight test item [g]

1

16.417

28.731

12.314

2

16.418

28.656

12.238

Table 3: Density of Scopolamine

Weight No.

Determined sample volume [cm^3]

Weight test item [g]

Temperature [°C]

Density [g/cm^3]

Relative Density [-]

1

9.61564

12.314

19.99

1.2806

1.2806

2

9.56306

12.238

19.99

1.2797

1.2797

 

 

mean:

19.99

1.2802

1.2802

 

 

absolute deviation

0.0

0.0009

0.0009

 

 

Relative deviation [%]

0.0

0.07

0.07

Conclusions:
The relative density was determined to be pSubstance (at 20°C)/pWater (compared to water at 4°C) = 1.2802 according to OECD Test Guidelines 109 (2012) and Regulation EC No. 440/2008 Part A. Method A.3.

Description of key information

The relative density of p substance (20°C)/p water (4°C) = 1.2802 was determined ( According to OECD Test Guidelines 109 (2012) and Regulation EC No. 440/2008 Part A. Method A.3).

Key value for chemical safety assessment

Relative density at 20C:
1.28

Additional information