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EC number: 200-917-8 | CAS number: 75-94-5
No reliable in vivo data are available for skin irritation/corrosion or eye irritation. However, based on the fact that this substance is a chlorosilane, so generates hydrogen chloride in the presence of moisture, it is expected to be corrosive. Therefore, in accordance with Column 2 of REACH Annex VIII, the in vivo skin irritation study and eye irritation study (required in Section 8.1.1 and 8.2.1) do not need to be conducted as the available information indicates that the substance meets the criteria for classification as corrosive to skin. Supporting data are available.
Trichloro(vinyl)silane is labelled 'R35 Causes severe burns' according the criteria of EU Directive 67/548/EEC and 'Skin Corr. 1A' under Regulation 1272/2008. It is assumed that substances that are corrosive to the skin are also damaging to the eyes, so there is no separate labelling for the eyes. There are no specific data for respiratory irritation. However, the pathology examination in the key acute inhalation study revealed signs of respiratory irritation/corrosion. The test substance is labelled as 'R37 Irritating to respiratory system', and the hazard statement 'EUH071 Corrosive to the respiratory tract' is proposed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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