Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2015
Report date:
2015

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Reference substance name:
Phosphoric acid, mono C16-20 (branched, even numbered) alkyl esters
Molecular formula:
unspecified
IUPAC Name:
Phosphoric acid, mono C16-20 (branched, even numbered) alkyl esters
Test material form:
liquid

Results and discussion

Preliminary study:
The preliminary test of OECD 111 (5 days incubation at 50°C at pH values 4, 7 and 9), the test item is considered to be hydrolytically stable at pH 4, 7 and 9.
The results of the preliminary tests are described in the table "total recovery of the test substances (in %).
Transformation products:
no
Total recovery of test substance (in %)open allclose all
% Recovery:
99.2
pH:
4
Temp.:
50 °C
Duration:
0 d
Remarks on result:
hydrolytically stable based on preliminary test
% Recovery:
100.1
pH:
7
Temp.:
50 °C
Duration:
0 d
Remarks on result:
hydrolytically stable based on preliminary test
% Recovery:
98
pH:
9
Temp.:
50 °C
Duration:
0 d
Remarks on result:
hydrolytically stable based on preliminary test
% Recovery:
101.7
pH:
4
Temp.:
50 °C
Duration:
5 d
Remarks on result:
hydrolytically stable based on preliminary test
% Recovery:
94
pH:
7
Temp.:
50 °C
Duration:
5 d
Remarks on result:
hydrolytically stable based on preliminary test
% Recovery:
102.4
pH:
9
Temp.:
50 °C
Duration:
5 d
Remarks on result:
hydrolytically stable based on preliminary test
Dissipation DT50 of parent compoundopen allclose all
Key result
pH:
4
Temp.:
50 °C
Remarks on result:
hydrolytically stable based on preliminary test
Key result
pH:
7
Temp.:
50 °C
Remarks on result:
hydrolytically stable based on preliminary test
Key result
pH:
9
Temp.:
50 °C
Remarks on result:
hydrolytically stable based on preliminary test

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Following the prelininary test of OECD 111 (5 days incubation at 50°C at pH values 4,7 and 9), the test item is considered to be hydrolytically stable at pH 4, 7 and 9.