Reaction mass of 3-phenyl-6-[(3-phenyl-3,4-dihydro-2H-1,3-benzoxazin-8-yl)methyl]-3,4-dihydro-2H-1,3-benzoxazine and 6,6'-methanediylbis(3-phenyl-3,4-dihydro-2H-1,3-benzoxazine)

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Study period:

This study was conducted between 20 September 2016 and 20 January 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: The study is considered to be a reliability 1 as it has been conducted according to OECD TG 102 using the method to determine the freezing point and in compliance with GLP.

Justification for type of information:

Please refer to the Read-Across justification document enclosed in chapter 13 for more details.

Reason / purpose for cross-reference:

read-across source

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

EC No. 440/2008 of 30 May 2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

27 July 2005

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

method to determine freezing temperature

Key result

Melting / freezing pt.:

> 37.2 - < 39.4 °C

Decomposition:

no

Sublimation:

no

Key result

Melting / freezing pt.:

> 310.3 - < 312.5 K

Decomposition:

no

Sublimation:

no

Discussion

The test item was analysed from sub ambient temperatures in order to obtain a stable baseline prior to the monitoring of the test item from ambient temperatures.

Determinations 1 and 2 were used to determine a suitable temperature range for the melting point determination, therefore, as the enthalpy of the change at approximately 40 °C is much smaller than the later endotherm, no integration was carried out.

As the test item shows a range of melting temperature the final results is reported as a melting range.

Conclusions:

The melting/freezing point of the test item was determined to be 37.2 - 39.4°C in a reliable GLP study according to OECD TG 102 using the the method to determine melting/freezing temperature.

Executive summary:

The general physico-chemical properties of Formaldehyde, reaction products with aniline, 4,4'-methylenebis[phenol] have been determined.

Melting/Freezing Point. In the range 37.2 to 39.4 °C (310.3 to 312.5 K) by differential scanning calorimetry using a method designed to be compatible with Method A.1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Description of key information

Melting/Freezing Point. In the range 37.2 to 39.4 °C (310.3 to 312.5 K) by differential scanning calorimetry using a method designed to be compatible with Method A.1 Melting/Freezing Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 102 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

This endpoint is coming from a read-across:

ARALDITE MT 35600/35610 is used as source to read across this endpoint in ARALDITE MT 35700 dossier (TARGET).

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:

37.2 °C