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Toxicological information

Endpoint summary

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Description of key information

A GPMT (Guinea Pig Maximisation Test) is available. Twenty male albino guinea pigs were used to test the sensitizing potential of 1,4-dihydroxyanthraquinone.

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Only two of the 20 guinea pigs tested reacted when given the challenge injection. The mean score for each of the two guinea pigs indicates a severe response.


Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available
Additional information:

In a guinea pig maximization test on 20 animals only 2 animals showed a positive reaction.

Justification for classification or non-classification

In a guinea pig maximization test on 20 animals only 2 animals showed a positive reaction.

According to CLP classification criteria (Regulation (EC) No 1272/2008) a classification is therefore not justified.