Registration Dossier

Physical & Chemical properties

Endpoint summary

Administrative data

Description of key information

Appearance :

On the basis of physical observation and using the sense of smell, Isopentyl propionate was determine to be a colorless liquid.

Melting point :

The Freezing point of Isopentyl propionate; CAS No. 105-68-0 was determined with freezing temperature method and it was determine to be less than -7.61 °C at 967.3 hPa.

Boiling Point :

The boiling point determination of Test item Isopentyl propionate (CAS No. 105-68-0 ) was done as per the test guideline OECD 103. The method followed was according to Siwoloboff. The mean boiling point was determine to be 158°C at 964.2 hPa.

Density :

The density of test item Isopentyl propionate (CAS No. 105-68-0) was determined following OECD Guideline 109 and according to the IS 4730 : 1994 (Reaffirmed 2010) – Method for Determination of Density of Liquids (First Revision) using glass pyknometer. The mean density of test item was  determine to be 0.8649 g/cm³ at 20°C and 964.1 hPa.

Particle size distribution :

The study does not need to be conducted because the substance is marketed or used in a non solid or granular form. It is concluded that chemical isopentyl propionate physically appears as a colorless liquid.

Vapour pressure :

Vapour pressure of isopentyl propionate is determine to be 1.3331 kPa at minimum temperature 51.27 Deg C & 202.6284 kPa at maximum temperature 187.34 Deg C.

Partition coefficient :

The Log Pow value was determined to be 3.365 ± 0.004 dimensionless at 25°C.This value indicates that the substance is hydrophilic in nature.

Water solubility :

The water solubility determination of test item Isopentyl propionate;CAS No.105-68-0 was done by spectrophotometric method. The water solubility was determine to be 194.505 mg/L at 25°C.

Surface tension :

Surface tension of isopentyl propionate is determine to be 0.02325 N/m at 25 Deg C.

Flash point :

The flash point determination of Isopentyl propionate (CAS No. 105-68-0)was done following closed cup method using Pensky-Martens flash point apparatus. The test was conducted in replicates and mean flash point was observed to be 41.3°C at 964.3 hPa.

Auto flammability :

Self-ignition temperature of isopentyl propionate which appear as liquid is determine to be 395 Deg C.

Flammability :

The study does not need to be conducted because the substance is a liquid .The study does not need to be conducted because the substance Isopentyl propionate is a flammable liquid in catagory 3 having a reported flash point of 41.3 degree C. Therefore it is not recommended to conduct testing for flammability. Thus, this end point was considered for waiver.

Explosiveness :

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.

Oxidizing properties :

The study does not need to be conducted because the organic substance contains oxygen or halogen atoms which are chemically bonded only to carbon or hydrogen and hence, the classification procedure does not need to be applied.

pH :

The pH determination of test item Isopentyl propionate (CAS No 105-68-0) was done following OECD guideline 122. pH of 1% w/v emulsion was measured with the help of pH meter and it was observed to be 4.81 at 25 °C.

Viscosity :

Kinematic viscosity (experimental) of Isopentyl propionate ( CAS No.105-68-0) at 20°C and 40°C is 13.7280 mm²/sec and 12.6720 mm²/s,respectively.

Dynamic viscosity (calculated) of Isopentyl propionate (CAS No.105-68-0) at 20°C and 40°C is 11.8733 mPa.S and 10.9600 mPa.S, respectively.

Additional information

Appearance :

On the basis of physical observation and using the sense of smell, Isopentyl propionate was determine to be a colorless liquid.

From the other reliable sources & authorative databases it is concluded that Isopentyl propionate physically appear as a colorless liquid having fruity odor such as pineapple-apricot which is near to key result.

Melting point :

The Freezing point determination of Isopentyl propionate (CAS No.105 -68 -0) was done using crushed ice and salt. No freezing was observed up to -7.61°C. Hence, the freezing point was inferred to be less than -7.61°C at 967.3 hPa.

From the different reliable sources & authorative database it is concluded that freezing point of Isopentyl propionate is between the range -70.1 to -73 Deg C as key result indicates that freezing point less than -7.61 Deg C.

Boiling Point :

The boiling point determination of Test item Isopentyl propionate (CAS No. 105-68-0 ) was done as per the test guideline OECD 103. The method followed was according to Siwoloboff. The mean boiling point was determine to be 158°C at 964.2 hPa.

From the different sources & authorative database boiling point of Isopentyl propionate is in between 160 to 161 Deg C which is near to the key value.

Density :

The density of test item Isopentyl propionate (CAS No. 105 -68 -0) was determined following OECD Guideline 109 and according to the IS 4730 : 1994 (Reaffirmed 2010) – Method for Determination of Density of Liquids (First Revision) using glass pyknometer. The mean density of test item was  determine to be 0.8649 g/cm³ at 20°C and 964.1 hPa.

From the different reliable sources & authorative databases it is concluded that density of Isopentyl propionate is in the range of 0.866 to 0.87 g/cm3 at various temperature conditions which is near to the key value.

Particle size distribution :

The study does not need to be conducted because the substance is marketed or used in a non solid or granular form. It is concluded that chemical isopentyl propionate physically appears as a colorless liquid.

Vapour pressure :

Vapour pressure of isopentyl propionate is determine to be 1.3331 kPa at minimum temperature 51.27 Deg C & 202.6284 kPa at maximum temperature 187.34 Deg C.

Partition coefficient :

The Log Pow value was determined to be 3.365 ± 0.004 dimensionless at 25°C.This value indicates that the substance is hydrophilic in nature.

Water solubility :

The water solubility determination of test item Isopentyl propionate (CAS No. 105-68-0) was done as per the OECD guideline 105 by spectrophotometric analytical method as per OECD 101. The solubility of (Isopentyl propionate of 105-68-0 )in water was determine to be 194.505 mg/L at 25°C. From the above water solubility value it is concluded that Isopentyl propionate moderately soluble in water.

Surface tension :

Surface tension of isopentyl propionate is determine to be 0.02325 N/m at 25 Deg C.

Flash point :

The flash point determination of Isopentyl propionate (CAS No. 105 -68 -0)was done following closed cup method using Pensky-Martens flash point apparatus. The test was conducted in replicates and mean flash point was observed to be 41.3°C at 964.3 hPa.

From the different reliable sources & authorative databases flash point of Isopentyl propionate is concluded in the range between 40 to 41 Deg C near to the key value.

Auto flammability :

Self-ignition temperature of isopentyl propionate which appear as liquid is determine to be 395 Deg C.

Flammability :

The study does not need to be conducted because the substance is a liquid .The study does not need to be conducted because the substance Isopentyl propionate is a flammable liquid in catagory 3 having a reported flash point of 41.3 degree C. Therefore it is not recommended to conduct testing for flammability. Thus, this end point was considered for waiver.

Explosiveness :

The study does not need to be conducted because there are no chemical groups present in the molecule which are associated with explosive properties.

Oxidizing properties :

The study does not need to be conducted because the organic substance contains oxygen or halogen atoms which are chemically bonded only to carbon or hydrogen and hence, the classification procedure does not need to be applied.

pH :

The pH determination of test item Isopentyl propionate (CAS No 105-68-0) was done following OECD guideline 122. pH of 1% w/v emulsion was measured with the help of pH meter and it was observed to be 4.81 at 25 °C.

Viscosity :

The viscosity determination of Test item Isopentyl propionate (CAS No. 105 -68 -0 ) was done as per the test guideline OECD 114 using Redwood Viscometer No. 1. Kinematic viscosity (experimental) of Test item at 20°C and 40°C is 13.7280 mm²/sec and 12.6720 mm²/s, respectively. Dynamic viscosity (calculated) of Test item at 20°C and 40°C is 11.8733 mPa.S and 10.9600 mPa.S, respectively.