Hydroxyprogesterone

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2015

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study without detailed documentation

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.3 (Relative Density)

GLP compliance:

no

Type of method:

pycnometer method

Type:

relative density

Density:

1.211 other: dimensionless

Temp.:

20 °C

Remarks on result:

other: mean value of 2 determinations

Literature data (CRC Handbook of Chemistry and Physics 75th Edition)

d (20, w) (density of water at 20 °C) = 0.9982 g/mL

d (4, w) (density of water at 4 °C) = 0.99997 g/mL

d (20, a) (density of air at 20 °C) = 0.0012 g/mL

Conclusions:

The density of the substance at 20 ºC was 1.211 g/cm3 and the relative density was 1.211.

Executive summary:

According to the OECD Guideline 109 (Density of Liquids and Solids) corresponding to A.3., Council Regulations EC No 440/2008 the solid sample was accurately weighed into a 20 mL pycnometer and by displacement of the solvent (n-heptan), its equivalent volume was determined. Finally, the density of the sample was calculated. The density at 20 ºC was 1.211 g/cm³and the relative density was 1.211.

Description of key information

The density of the substance at 20 ºC is 1.211 g/cm3 and the relative density 1.211.

Key value for chemical safety assessment

Relative density at 20C:

1.211