Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1996
Report date:
1996

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method B.1 (Acute Toxicity (Oral))
Deviations:
no
Test type:
standard acute method
Limit test:
no

Test material

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Route of administration:
oral: gavage

Results and discussion

Effect levelsopen allclose all
Key result
Sex:
male/female
Dose descriptor:
LD50
Effect level:
156 mg/kg bw
Based on:
test mat.
95% CL:
>= 90.5 - <= 270
Remarks on result:
other:
Sex:
female
Dose descriptor:
LD50
Effect level:
171 mg/kg bw
Based on:
test mat.
95% CL:
>= 114 - <= 257
Sex:
male
Dose descriptor:
LD50
Effect level:
149 mg/kg bw
Based on:
test mat.
95% CL:
>= 110 - <= 202

Applicant's summary and conclusion

Categories Display