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Ecotoxicological information

Long-term toxicity to fish

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Description of key information

Long-term toxicity to fish: 60-d post-hatch NOEC ≥0.0079 mg/l (time weighted mean measured) (highest concentration tested) (OECD 210), based on hatching, larval survival, abnormal appearance and behaviour in Oncorhynchus mykiss, read across from an analogous/structurally related substance, decamethyltetrasiloxane (L4, CAS 141-62-8).

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
7.9 µg/L

Additional information

There are no reliable long-term fish toxicity data available for tetradecamethylhexasiloxane (L6, CAS 107-52-8), therefore good quality data for an appropriate structural analogue, decamethyltetrasiloxane (L4, CAS 141-62-8), have been read across.

 

A 60-d post-hatch NOEC of ≥0.0079 mg/l (time weighted mean measured) has been determined for the effects of the analogous substance, decamethyltetrasiloxane (CAS 141-62-8) on hatching, larval survival, abnormal appearance and behaviour in Oncorhynchus mykiss in the fish early-life stage test (OECD 210). In view of the exposure regime it is likely that the test organisms were exposed primarily to the tested substance rather than its degradation products. 

 

Refer to IUCLID Section 6 endpoint summary (CSR Section 7.0) for further information on the approach to chemical safety assessment for this registration substance, and justification for read-across used.