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EC number: - | CAS number: -
The test substance was tested for eye irritation in an in vivo OECD 405 study. The substance was instilled as is in the right eyes of three New Zealand albino rabbits. The left eyes were untreated and used as controls. Within one hour after test substance instillation, all three treated eyes exhibited 'positive' conjuctivitis. By 24 hours, corneal opacity developed in two animals. There was no iritis observed in any treated eyes. The overall incidence and severity of irritation decreases gradually with time. Positive irritation cleared from all three treated eyes by Day 4. One animal was free of ocular irritation by Day 7 and two animals were free of ocular irritation by Day 14.
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