Registration Dossier

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Documentation insufficient for assessment.

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Anesthetic properties of a series of fluorinated compounds. I. Fluorinated hydrocarbons
Author:
Van Poznak A and Artusio JF Jr.
Year:
1960
Bibliographic source:
Toxicol. Appl. Pharmacol., 2:363-373
Reference Type:
secondary source
Title:
SIDS Initial Assessment Report for SIAM 22, 1,1-Difluoroethane (HFC-152a), CAS No: 75-37-6
Author:
OECD SIDS
Year:
2006
Bibliographic source:
UNEP Publications

Materials and methods

Type of study / information:
Inhalation in humans.
Endpoint addressed:
acute toxicity: inhalation
Principles of method if other than guideline:
The test substance was inhaled briefly by several volunteers.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Results:
The test substance was inhaled briefly by several volunteers at 50000 ppm, who noted good analgesia and impending loss of consciousness.

Applicant's summary and conclusion

Executive summary:

The test substance was inhaled briefly by several volunteers at 50000 ppm, who noted good analgesia and impending loss of consciousness.