Registration Dossier
Registration Dossier
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EC number: 200-866-1 | CAS number: 75-37-6
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Anesthetic properties of a series of fluorinated compounds. I. Fluorinated hydrocarbons
- Author:
- Van Poznak A and Artusio JF Jr.
- Year:
- 1 960
- Bibliographic source:
- Toxicol. Appl. Pharmacol., 2:363-373
- Reference Type:
- secondary source
- Title:
- SIDS Initial Assessment Report for SIAM 22, 1,1-Difluoroethane (HFC-152a), CAS No: 75-37-6
- Author:
- OECD SIDS
- Year:
- 2 006
- Bibliographic source:
- UNEP Publications
Materials and methods
- Type of study / information:
- Inhalation in humans.
- Endpoint addressed:
- acute toxicity: inhalation
- Principles of method if other than guideline:
- The test substance was inhaled briefly by several volunteers.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1,1-difluoroethane
- EC Number:
- 200-866-1
- EC Name:
- 1,1-difluoroethane
- Cas Number:
- 75-37-6
- Molecular formula:
- C2H4F2
- IUPAC Name:
- 1,1-difluoroethane
Constituent 1
Results and discussion
- Results:
- The test substance was inhaled briefly by several volunteers at 50000 ppm, who noted good analgesia and impending loss of consciousness.
Applicant's summary and conclusion
- Executive summary:
The test substance was inhaled briefly by several volunteers at 50000 ppm, who noted good analgesia and impending loss of consciousness.
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