Lavender, Lavandula hybrida, ext.

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

07 December 2016-22 March 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

The study was conducted according to an internationally recognised method, and under GLP. The substance is considered to be adequately characterised. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

UK GLP compliance programme (inspected on 05 July 2016 / signed on 28 October 2016)

Type of method:

air comparison pycnometer (for solids)

Key result

Type:

density

Density:

979 kg/m³

Temp.:

19 °C

Key result

Type:

relative density

Remarks:

D20/4

Density:

0.979 other: unitless

Temp.:

19 °C

Calibration

The pressure readings and the calculated volume for the reference and sample cells are shown in the following table:

Determination	P1 [psig]	P2 [psig]	P3 [psig]	P4 [psig]	Reference Cell Volume [cm3]	Sample Cell Volume [cm3]
1	17.057	6.461	17.552	8.701	90.821	148.945
2	17.386	6.588	17.105	8.480	90.939	149.053
3	17.078	6.475	17.068	8.462	91.149	149.259

Mean reference cell volume : 90.970 cm3 (standard deviation 0.166)

Mean sample cell volume : 149.086 cm3 (standard deviation 0.160)

Sample:

The pressure readings and volumes obtained for the vessel and the vessel containing the test itemare shown in the following table:

Determination	Test	Vessel			Vessel and Test Item
		P1(sample)	P2(sample)	Volume	P3(sample)	P4(sample)	Volume
		(psig)	(psig)	(cm3)	(psig)	(psig)	(cm3)
1	A	17.038	6.859	14.084	17.074	7.966	45.075
	B	17.016	6.850	14.079	17.003	7.939	45.225
	C	17.075	6.873	14.054	17.009	7.943	45.255
2	A	17.063	6.874	14.246	17.150	8.014	45.380
	B	17.039	6.864	14.235	17.015	7.944	45.211
	C	17.006	6.852	14.278	17.084	7.976	45.205

The calculated mean volumes and densities are shown in the following table:

Determination	Mean Volume of vessel (cm3)	Mean Volume of vessel and Test item (cm3)	Volume of Test Item (cm3)	Density (kg/m3)
1	14,072	45,185	31,113	982
2	14,253	45,265	31,012	976

Mean density : 979kg/m3 (SD = 4.44)

relative density, D20/4 : 0.979

Temperature: 19.0 +/-1.0°C

The results from the duplicate determinations showed reproducibility of less than ± 20 kg/m3; therefore, the results were considered acceptable.

Conclusions:

The density of the test item was determined to be 979 kg/m3 at 19.0 ± 1.0 ºC. The
corresponding relative density, D20/4 was calculated to be 0.979.
The test substance is less dense than water.

Executive summary:

The density of the test substance was measured under GLP according OECD 109 / EU A3 guideline, using the gas comparison pycnometer method.

After calibration, two independent samples were measured in triplicate. The mean density was calculated and converted to relative density towards water at 4°C.

As the difference between both determinations was below 20 kg/m³ , the results were considered as valid and the mean density at 19.0 °C was calculated. This result was then converted to relative density towards water at 4 °C.

Mean density: 0.979 x 10³kg/m³ at 19.0 ± 1°C

Mean relative density (D20/4) : 0.979

Description of key information

The density of the test item has been determined to be 0.979 x 10³kg/m³at 19.0 ± 1 °C and a relative density (D20/4) of 0.979.

Key value for chemical safety assessment

Relative density at 20C:

0.979

Additional information

A reliable GLP experimental study, conducted according to a recognized OECD/EC method (gas comparison pycnometer method), is available. It is considered as a key study.