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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
experimental dates: July 02-04, 2008
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognized method, and under GLP. No deviation was reported. Test substance is adequately specified. Therefore full validation applies.
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
July 27, 1995
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Version / remarks:
EEC Directive 92/69, December 1992
GLP compliance:
yes (incl. QA statement)
Remarks:
signed on 09 June 2008
Type of method:
method to determine freezing temperature
Key result
Melting / freezing pt.:
< -76 °C

During the main tests, the samples were cooled down from room temperature to about -76°C.

The test item increased in viscosity but was still movable. Therefore, no clear freezing point could be determined within the temperature range.

The freezing point must be below -76°C.

Conclusions:
No further testing required (< -20°C).
Executive summary:

The freezing point of the test substance was determined under GLP according to OECD 102 / EU A1 guideline. The determination was carried out in duplicate.

The test item did not freeze during cooling down to -76°C. Viscosity increased, but the sample was still movable.

The freezing temperature of the test substance has been determined to be less than -76°C.

Description of key information

Freezing point < -76°C.

No further testing required.

Key value for chemical safety assessment

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. It is considered as a key study. As no crystallisation was observed down to -76°C, the result is expressed as a limit value, and cannot be retained as key data.