Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
relative self-ignition temperature (solids)
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because the substance is a solid having a melting point <= 160°C
Justification for type of information:
JUSTIFICATION FOR DATA WAIVING
The substance has a melting point of 90.4 °C (see IUCLID section 4.2) and hence, testing can be omitted.
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2016-06-10
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
GLP compliance:
no
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
90.4 °C
Conclusions:
The study was conducted under a scientifically reasonable method (DSC) according to OECD 102 with sufficient documentation to conclude that the study was well performed. Hence, the melting point of 90.4°C can be considered as reliable.
Executive summary:

The melting point of Isobutyl 4-chloro-3,5-diaminobenzoate was determined to be 90.4 °C in a OECD 102 study.

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion