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EC number: 441-570-4 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 10th November to 17 December 1999
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: study conducted in a GLP compliant laboratory according to accepted regulatory guidelines
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Deviations:
- no
- GLP compliance:
- yes
- Analytical monitoring:
- yes
- Details on sampling:
- - Concentrations: 100, 180, 320, 560 and 1000 mg/L
- Sampling method:Water samples were taken from the control and all surviving test groups at 0,24 (old media), and 96 hours (old media) for quantitative analysis.
- Sample storage conditions before analysis: Duplicate samples and samples at 24 (fresh media), 48 and 72 hours (fresh and old media) were
taken and stored frozen (approximately -20DC) for further analysis if necessary. - Details on test solutions:
- Identity and concentration of auxiliary solvent for dispersal: None
- Test organisms (species):
- Oncorhynchus mykiss (previous name: Salmo gairdneri)
- Details on test organisms:
- TEST ORGANISM
- Common name: Juvenile rainbow trout
- Strain: N/a
- Source: Reputable commercial supplier
- Age at study initiation (mean and range, SD):
- Length at study initiation (length definition, mean, range and SD): 4.2 cm (sd = 0.2)
- Weight at study initiation (mean and range, SD): 0.82 g (sd = 0.10)
- Method of breeding: N/a
- Feeding during test: Not feed during the definitive test
- Food type:
- Amount:
- Frequency:
ACCLIMATION
- Acclimation period: 7days
- Acclimation conditions (same as test or not): Yes
- Type and amount of food: commercial trout pellets
- Feeding frequency:daily which was discontinued 24 hours prior to the start of the definitive study
- Health during acclimation (any mortality observed): ca 1% mortality in 7 days period
QUARANTINE (wild caught)
- Duration:
- Health/mortality: - Test type:
- semi-static
- Water media type:
- freshwater
- Hardness:
- 100 mg CaCO3/L
- Test temperature:
- 14C
- pH:
- 7.6 - 8.1
- Dissolved oxygen:
- 9.3 - 9.8 mg O2/L
- Salinity:
- N/a
- Nominal and measured concentrations:
- Analysis of the test solutions at 0, 24 and 96 hours showed the measured test concentrations to be below the limit of quantitation of the analytical method. These results were in-line with pre-study recovery analysis performed on filtered WAFs at a loading rate of 1000 mg/I which also showed measured test concentrations of below the limit of quantitation of the analytical method.
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LL50
- Effect conc.:
- 400 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: 95% CL
- Key result
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 180 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Details on results:
- %Concentration loss over test: 8 ...
- Validity criteria fulfilled:
- yes
- Conclusions:
- The acute toxicity of the test material to the freshwater fish rainbow trout (Oncorhynchus mykiss) has been investigated and gave a 96-Hour LLso* value of 400 mg/I loading rate filtered WAF with 95% confidence limits of 360 - 450 mg/l loading rate filtered WAF. The No Observed Effect Loading rate
was 180 mg/I loading rate filtered WAF.
Reference
Description of key information
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 400 mg/L
Additional information
The LC50 value refers to nominal loading level resulting from water accomodated fraction (WAF). Water solubility of the substance is < 0.1 mg/l.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.

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