Registration Dossier
Registration Dossier
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EC number: 201-854-9 | CAS number: 88-73-3
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: migrated IUCLID4 data set
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- Linch, A.L.
- Year:
- 1 974
- Bibliographic source:
- Am. Ind. Hyg. Assoc. J. 35, 426-432
Materials and methods
Test material
- Reference substance name:
- 1-chloro-2-nitrobenzene
- EC Number:
- 201-854-9
- EC Name:
- 1-chloro-2-nitrobenzene
- Cas Number:
- 88-73-3
- Molecular formula:
- C6H4ClNO2
- IUPAC Name:
- 1-chloro-2-nitrobenzene
Constituent 1
Results and discussion
Any other information on results incl. tables
Based on clinical and laboratory evaluation of cyanosis cases during a 10-year period a number of cyanogenic aromatic nitro compounds were ranked in descending order of relative hazard relating to their cyanogenic potential observed in exposed industrial workers (rank 1 = most potent, rank 13 = least potent):
o-chloronitrobenzene was classified in rank 7;
laboratory evaluation showed that total oxygenatable haemoglobin in some cases, notably after be expected from methaemoglobin analysis (unspecified route of absorption)
Applicant's summary and conclusion
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