Registration Dossier
Registration Dossier
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EC number: 201-854-9 | CAS number: 88-73-3
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study. Adopted according to OECD SIDS. The original source is available and has been reviewed.
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 990
- Reference Type:
- secondary source
- Title:
- 1-Chloro-2-nitrobenzene CAS: 88-73-3, SIDS Initial Assessment Report
- Author:
- OECD
- Year:
- 2 001
- Bibliographic source:
- UNEP publications
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- Version / remarks:
- (1984)
- Principles of method if other than guideline:
- Note to data access: The study report belongs to UBA (governmental agency), so it is publicly available.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-chloro-2-nitrobenzene
- EC Number:
- 201-854-9
- EC Name:
- 1-chloro-2-nitrobenzene
- Cas Number:
- 88-73-3
- Molecular formula:
- C6H4ClNO2
- IUPAC Name:
- 1-chloro-2-nitrobenzene
- Details on test material:
- IUCLID4 Test substance: other TS: no purity given
- Name of test material (as cited in study report): 1-chlor-2-nitrobenzol
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- fish length: 2 cm
Study design
- Test type:
- flow-through
- Total exposure duration:
- 96 h
Test conditions
- Test temperature:
- 23 ± 1 °C
- pH:
- pH (dilution water) 8.15 ± 0.2
- Nominal and measured concentrations:
- nominal: 0, 3.4, 6.7, 12.5, 25, 50 mg/L
measured: 0, 3.5, 6.69, 12.3, 24.9, 52.2 mg/L - Details on test conditions:
- - 14 h light / 10 h dark
- 10 fish per concentration step
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 34.8 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- 34.6 mg/L
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
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