1-chloro-2-nitrobenzene

Bioaccumulation: aquatic / sediment

Administrative data

Endpoint:

bioaccumulation in aquatic species: fish

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Test procedure according to national standards. Adopted according to OECD SIDS. The original source is available and has been reviewed.

Data source

Reference

Reference 1

Reference Type:

study report

Title:

Unnamed

Year:

1992

Reference 2

Reference Type:

secondary source

Title:

1-Chloro-2-nitrobenzene CAS: 88-73-3, SIDS Initial Assessment Report

Author:

OECD

Year:

2001

Bibliographic source:

UNEP publications

Materials and methods

Test guideline

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)

Principles of method if other than guideline:

- the test was conducted in accordance with "Bioaccumulation test of chemical substance in fish and shellfish" (Japanese Guideline by MITI, 1974)
- this guideline corresponds to OECD 305 C: Bioaccumulation: Degree of Bioconcentration in Fish (1981)

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

1-chloro-2-nitrobenzene

EC Number:

201-854-9

EC Name:

1-chloro-2-nitrobenzene

Cas Number:

88-73-3

Molecular formula:

C6H4ClNO2

IUPAC Name:

1-chloro-2-nitrobenzene

Details on test material:

IUCLID4 Test substance: other TS: o-chloronitrobenzene (CAS-No. 88-73-3)
- Name of test material (as cited in study report): o-Chloronitrobenzene
- Analytical purity: no data

Sampling and analysis

Details on sampling:

- water analyzed twice a week
- fish every two weeks

Test organisms

Test organisms (species):

Cyprinus carpio

Details on test organisms:

Weight/length of exposed fish: 30g / 10cm
lipid content: 2-6%

Study design

Test type:

flow-through

Total exposure / uptake duration:

56 d

Test conditions

Test temperature:

25 °C

Nominal and measured concentrations:

test concentrations nominal: 0.025 mg/L and 0.25 mg/L

Results and discussion

Bioaccumulation factor

Bioaccumulation factor 1

Type:

BCF

Value:

7.4 - 22.3

Remarks on result:

other: Conc.in environment / dose:0.025 mg/L

Bioaccumulation factor 2

Type:

BCF

Value:

7 - 20.8

Remarks on result:

other: Conc.in environment / dose:0.25 mg/L

Any other information on results incl. tables

OECD SIDS (2001):

Measured bioconcentration factors (BCF) determined for fish (Cyprinus carpio) according to OECD guideline 305 C, were in the range of 7.0 - 22.3. 1-Chloro-2-nitrobenzene concentrations of 0.25 and 0.025 mg/L had been tested. Thus no significant potential for bioaccumulation of 1-chloro-2-nitrobenzene in aquatic organisms is indicated (MITI 1992).