Registration Dossier
Registration Dossier
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EC number: 291-063-5 | CAS number: 90320-37-9 Extractives and their physically modified derivatives such as tinctures, concretes, absolutes, essential oils, oleoresins, terpenes, terpene-free fractions, distillates, residues, etc., obtained from Prunus amygdalus sativa, Rosaceae.
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- December 2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- The study was conducted according to an internationally recognised method. No deviation was reported. Test substance is adequately specified. Therefore full validation applies.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 017
- Report date:
- 2017
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- not specified
- GLP compliance:
- no
- Type of method:
- flask method
Test material
- Reference substance name:
- Almond, sweet, ext.
- EC Number:
- 291-063-5
- EC Name:
- Almond, sweet, ext.
- Cas Number:
- 90320-37-9
- IUPAC Name:
- Almond, sweet, ext.
- Test material form:
- solid: particulate/powder
- Details on test material:
- - Appearance: white powder
- Storage: in a dark place at room temperature
- Batch : 16 187
- Manufacturing date: July 5th 2016
- Expiry date: July 5th 2018
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- ca. 350 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 520 g/L
- Temp.:
- 30 °C
- pH:
- ca. 8
Applicant's summary and conclusion
- Conclusions:
- A non-GLP study using flask method according to OECD method 105 and EU. A.6. was conducted to determine the water solubility of the test item.
The water solubility of the test item was determined as 350 g/L at 30 )C ± 0.5°C (pH=8).
The conditions of the test were:
- loading rate of 520 ± 1 g/L
- a water content of 6.0% w/w of POLYLIFT AT (dry matter result obtained on the powder). - Executive summary:
A non-GLP study using flask method according to OECD method 105 and EU. A.6. was conducted to determine the water solubility of the test item.
The water solubility of the test item was determined as 350 g/L at 30 °C ± 0.5°C (pH=8).
The conditions of the test were:
- loading rate of 520 g/L ± 1 g/L
- a water content of 6.0% w/w of POLYLIFT AT (dry matter result obtained on the powder).
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