Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
developmental toxicity
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
FMC Corporation
Year:
1972
Bibliographic source:
Niagara Chemical Division, Unpublished data. Ind. BIO-TEST Labs IBT No. B1056, Hoechst AG Report No. 72.0139 (cited in IUCLID (2000). IUCLID Dataset, o-phenylenediamine, February 20).

Materials and methods

Test guideline
Guideline:
other: guideline not reported

Test material

Constituent 1
Reference substance name:
Thiodan technical
IUPAC Name:
Thiodan technical

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified
Duration of treatment / exposure:
gestation days 6-15
Frequency of treatment:
daily
Control animals:
yes

Results and discussion

Results (fetuses)

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
not specified

Any other information on results incl. tables

Did not produce maternal, feto- or embryotoxicity and was not teratogenic.

Applicant's summary and conclusion

Conclusions:
Did not produce maternal, feto- or embryotoxicity and was not teratogenic.
Executive summary:

Did not produce maternal, feto- or embryotoxicity and was not teratogenic.