Registration Dossier

Administrative data

Endpoint:
developmental toxicity
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
FMC Corporation
Year:
1972
Bibliographic source:
Niagara Chemical Division, Unpublished data. Ind. BIO-TEST Labs IBT No. B1056, Hoechst AG Report No. 72.0139 (cited in IUCLID (2000). IUCLID Dataset, o-phenylenediamine, February 20).

Materials and methods

Test guideline
Guideline:
other: guideline not reported

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified
Duration of treatment / exposure:
gestation days 6-15
Frequency of treatment:
daily
Control animals:
yes

Results and discussion

Results (fetuses)

Fetal abnormalities

Abnormalities:
not specified

Overall developmental toxicity

Developmental effects observed:
not specified

Any other information on results incl. tables

Did not produce maternal, feto- or embryotoxicity and was not teratogenic.

Applicant's summary and conclusion

Conclusions:
Did not produce maternal, feto- or embryotoxicity and was not teratogenic.
Executive summary:

Did not produce maternal, feto- or embryotoxicity and was not teratogenic.